I've just been fit at Mizuno for some MP57's. My lie angle is 2 up.

Does the lie of your irons have any relationship with your putter?

I currently play either a Newport 2.5 (35") or an original Circa 62 No.3 (35")

Any help or advice would be appreciated.

I would say there is no correlation. My irons are 4 degrees upright, however my putter is standard. On the other hand, Chris DiMarco has standard lie irons, but his putter is 4 or 5 degrees upright.

No correlation

there is no correlation for the simple fact that these clubs operate on completely different planes... the putting stroke is completely different than the standard full swing that the rest of your clubs have been fit for....

I would get your putter fit as well. I use a Flat lie on my putter as I do in my irons. The lie of your putter is just as important as the lie on your irons, so if the toe of your putter is off the ground or the heel, you need the lie adjusted. The lie on your irons plays no part in the lie on your putter because they can differ depending on your setup and stroke, however you still have to check the lie on your putter.

Thanks all for taking time out to post the info.